tisdag 4 februari 2014

Demens av värktabletter?

April 23, 2009 — Contrary to previous reports, a new study suggests that nonsteroidal anti-inflammatory drugs (NSAIDs) do not prevent dementia, including Alzheimer's disease (AD), but may simply delay disease onset.
The study showed that compared with nonuse of NSAIDs, heavy use of these drugs was associated with a 66% increased risk for dementia.
The authors speculate that earlier research found less dementia in NSAID users because those studies included relatively young populations, and therefore the true action of NSAIDs delays the onset of dementia rather than suppressing the disorder.
However, at this point this is merely a hypothesis, and the question of why this study shows NSAIDs may cause dementia while other research shows the opposite is still an open one, said study author John C. S. Breitner, MD, from the Department of Veterans Affairs and the University of Washington School of Medicine, in Seattle.
"There's no escaping the fact that this study found that NSAID users have more dementia in their 80s than nonusers. But this and earlier studies do not form a basis for clinical-practice decisions," Dr. Breitner told Medscape Neurology.

Läs hela artikeln här:  http://www.medscape.com/viewarticle/701813

Please note:
Heavy NSAID users were 66% more likely to develop dementia.
What is the definition of heavy use: appr. 6 advil/ibuprofen etc. per day.

Febernedsättande, antiinflammatorisk och smärtstillande läkemedel kan om det tas i stora doser om 6 tabletter per dag innebära en ökad risk för utveckling av demens.
Lite skrämmande att tänka tanken att det läkemedel som ges till dementa i stora mängder även kan orsaka sjukdomen, eller hur?


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