Prostate disease and HPV
The exact role of HPV in the development of benign and malignant lesions of the prostate is unclear. However, several studies have demonstrated an association between HPV and prostate disease, including prostate cancer. For this reason, treatment of men who are possible carriers of HPV takes on a much greater significance.
Källa: http://www.health-science-report.com/alotek/topics3/article41/
Källa: http://newsroom.unsw.edu.au/news/science/two-virus-link-prostate-cancer
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The exact role of HPV in the development of benign and malignant lesions of the prostate is unclear. However, several studies have demonstrated an association between HPV and prostate disease, including prostate cancer. For this reason, treatment of men who are possible carriers of HPV takes on a much greater significance.
Källa: http://www.health-science-report.com/alotek/topics3/article41/
News |
Science
Two-virus link to prostate cancer
01 August 2012
Two common viruses known to be associated with human cancers are both present – and may even be collaborating with each other - in most male prostate cancers, a new study suggests.
The research has revealed that both the human papilloma virus (HPV) and Epstein Barr virus (EBV) are present in more than half of malignant prostate cancers found in Australian men, as well as in a high proportion of benign and normal prostate samples.
Details of the study, led by Associate Professor Noel Whitaker and Professor James Lawson, of the UNSW School of Biotechnology and Biomolecular Sciences, are published in the journal The Prostate. The research team included other UNSW researchers and colleagues from the Department of Forensic Medicine Sydney South West Area Health Service and Douglass, Hanly, Moir Pathology.
“Recent unpublished experimental evidence by other researchers suggests that HPV and EBV can collaborate to promote the survival and proliferation of cancer cells, so our findings may well have important implications for understanding and preventing prostate cancer,” says Professor Whitaker.
“Significantly, in our prostate samples we found a high-risk strain known as HPV 18, which is known to be associated with other human cancers.
“HPV 18 is a common high-risk strain in Australia and is a specific target of the Gardasil vaccine now offered free to teenage girls to protect against cervical cancer.
The research has revealed that both the human papilloma virus (HPV) and Epstein Barr virus (EBV) are present in more than half of malignant prostate cancers found in Australian men, as well as in a high proportion of benign and normal prostate samples.
Details of the study, led by Associate Professor Noel Whitaker and Professor James Lawson, of the UNSW School of Biotechnology and Biomolecular Sciences, are published in the journal The Prostate. The research team included other UNSW researchers and colleagues from the Department of Forensic Medicine Sydney South West Area Health Service and Douglass, Hanly, Moir Pathology.
“Recent unpublished experimental evidence by other researchers suggests that HPV and EBV can collaborate to promote the survival and proliferation of cancer cells, so our findings may well have important implications for understanding and preventing prostate cancer,” says Professor Whitaker.
“Significantly, in our prostate samples we found a high-risk strain known as HPV 18, which is known to be associated with other human cancers.
“HPV 18 is a common high-risk strain in Australia and is a specific target of the Gardasil vaccine now offered free to teenage girls to protect against cervical cancer.
Källa: http://newsroom.unsw.edu.au/news/science/two-virus-link-prostate-cancer
Uppdatering i ämnet följer....
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